|Certificates: Molecular Biophysics, Molecular Biophysics|
|Course Cluster: Health Studies, Integrated Design, Engineering & Applied Science Minor|
This course aims to provide a framework for understanding three-dimensional structures of proteins, nucleic acids, and their complexes. The first half of the course emphasizes structural modules and topological patterns in major classes of proteins and nucleic acids. The second part of the course covers novel structural motifs, such as helix-turn-helix, zinc-finger, and leucine zipper, that are responsible for recognition of specific nucleotide sequences in nucleic acids by proteins. Analysis of structures using tools available on the Web and independent exploration of protein and nucleic acid databases are strongly encouraged.
||Gen Ed Area Dept:
|Course Format: Lecture / Discussion||Grading Mode: Student Option|
||Prerequisites: [MB&B181 or BIOL181] OR [MB&B191 or BIOL191]
||Fulfills a Major Requirement for: (CHEM-Track B)(CIS)(IDEA-MN)(MB&B)
||Past Enrollment Probability: 90% or above
|Major Readings: Wesleyan RJ Julia Bookstore
Branden and Tooze, INTRODUCTION TO PROTEIN STRUCTURE
Selected journal articles.
|Examination and Assignments: |
One midterm exam and final exam. Homework assignments.
|Additional Requirements and/or Comments: |
Prerequisite can be an equivalent course to MB&B205. This course is recommended for all students interested in structural biology, especially those majoring in biological chemistry, molecular biology and biochemistry, and molecular biophysics.
|Instructor(s): Russu,Irina M. Times: ..T.R.. 01:20PM-02:40PM; Location: TBA|
|Total Enrollment Limit: 60||SR major: 15||JR major: 15|| || |
|Seats Available: 44||GRAD: 10||SR non-major: 10||JR non-major: 5||SO: 5||FR: 0|