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Biological Thermodynamics

CHEM 386
Fall 2014 not offered
Crosslisting: MB&B 386
Certificates: Molecular Biophysics

This course is addressed to undergraduate and graduate students interested in biological chemistry and structural biology. The course presents thermodynamic methods currently used to relate structure to function in biological molecules. Topics include binding curves, chemical ligand linkages, binding polynomial, cooperativity, site-specific binding processes, and allosteric effects. Several models for allosteric systems, such as the Monod-Wyman-Changeux model, the induced-fit model, and the Pauling model, are analyzed in detail. Applications of these models are illustrated for functional regulation of respiratory proteins and for protein-nucleic-acid complexes involved in control of gene expression.
Credit: 1 Gen Ed Area Dept: NSM CHEM
Course Format: Lecture / DiscussionGrading Mode: Student Option
Level: UGRD Prerequisites: (MATH121 AND MATH122)
Fulfills a Major Requirement for: None

Last Updated on APR-18-2014
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