Fall 2018 not offered
MB&B 333, BIOL 533, BIOL 333|
|Certificates: Informatics and Modeling|
This course aims to develop a genome perspective on transcriptional gene regulation. The genome sequence, now completed in a number of organisms, is described as a blueprint for development. More than simply a parts list (i.e., genes), this blueprint is an instruction manual as well (i.e., regulatory code). A next critical phase of the genome project is understanding the genetic and epigenetic regulatory codes that operate during development. Through a combination of lectures and discussion of primary literature, this course will explore current topics on promoters and transcription factors, chromatin structure, regulatory RNA, chromosomal regulatory domains, and genetic regulatory networks. An overarching theme is how genomes encode and execute regulatory programs as revealed by a global systems biology approach in modern genomics research.
||Gen Ed Area Dept:
|Course Format: Lecture / Discussion||Grading Mode: Graded|
||Prerequisites: [BIOL182 or MB&B182]
||Fulfills a Major Requirement for: (BIOL)(MB&B)
Two recently-published papers per week.
|Examination and Assignments: |
Paper presentations, tests, and homework assignments.
|Additional Requirements and/or Comments: |
Prerequisite for BIOL 206 is based on the assumption that students will have broad familiarity with basic molecular biology.