Cells contain elaborate systems for sensing their environment and for communicating with neighbors across the membrane barrier. This class will explore molecular aspects of signal transduction in prokaryotic and eukaryotic cells. Topics will include membrane receptors, GPCRs, kinases, phosphorylation, ubiquitination, calcium signaling, nuclear receptors, quorum sensing, and human sensory systems. We will integrate biochemical functional approaches with structural and biophysical techniques.
||Gen Ed Area Dept:
|Course Format: Lecture / Discussion||Grading Mode: Graded|
||Prerequisites: [MB&B208 or BIOL208]
||Fulfills a Major Requirement for: (BIOL)(MB&B)
||Past Enrollment Probability: 90% or above
|Major Readings: Wesleyan RJ Julia Bookstore
Cell Signaling: Principles and mechanisms by Lim, Mayer, and Pawson.
|Examination and Assignments: |
There will be quizzes, exams, one scientific paper presentation, and some homework.
|Instructor(s): Olson,Rich Times: .M.W... 02:50PM-04:10PM; Location: SHAN201; |
|Total Enrollment Limit: 30||SR major: 15||JR major: 15|| || |
|Seats Available: 26||GRAD: X||SR non-major: 0||JR non-major: 0||SO: 0||FR: 0|